Across TCGA pan-cancer cohorts, EIF4A1P8 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of EIF4A1P8’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where EIF4A1P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EIF4A1P8 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, COAD, and LIHC are the cancer types where EIF4A1P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF4A1P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.049	.006	6	view →
COAD	Female	IV	+0.130	.036	3	view →
LIHC	All	II,III,IV	+0.022	.010	2	view →
THCA	Female	All	−0.025	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: EIF4A1P8 RNA expression & survival · all EIF4A1P8 data types