EIF4A1P6

Across TCGA pan-cancer cohorts, EIF4A1P6 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated EIF4A1P6 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher EIF4A1P6 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EIF4A1P6 expression acts as an unfavorable survival marker, although some lineages such as READ and THYM show a favorable association.

BRCA, LUSC, and ACC are the cancer types where EIF4A1P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Quartile	II,III,IV	0.320	0.583	.002	24	view →
LUSC	OS	Tertile	II,III,IV	0.650	0.942	.002	23	view →
ACC	OS	Tertile	All	0.733	0.931	.011	21	view →
STAD	OS	Tertile	II,III,IV	0.471	0.701	.015	18	view →
MESO	OS	Median	IV	0.350	0.751	.006	18	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
KIRC	DFS	Quartile	IV	0.270	0.579	.005	16	view →
READ	DFS	Tertile	All	1.000	0.629	.004	15	view →
THYM	DFS	Tertile	All	0.977	0.814	.008	13	view →
LUAD	DFS	Median	All	0.736	0.619	.007	12	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	9	view →
COAD	DFS	Quartile	All	0.805	0.460	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

EIF4A1P6–BRCA (DFS)

Open the BRCA breakdown →