EIF4A1P4

Across TCGA pan-cancer cohorts, EIF4A1P4 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated EIF4A1P4 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher EIF4A1P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EIF4A1P4 expression acts as an unfavorable survival marker, although some lineages such as READ and COAD show a favorable association.

UCS, ACC, and KIRC are the cancer types where EIF4A1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	III,IV	0.220	0.623	<.001	78	view →
ACC	DFS	Tertile	All	0.165	0.682	<.001	73	view →
KIRC	DFS	Tertile	III,IV	0.372	0.629	.002	63	view →
LUAD	OS	Median	All	0.571	0.763	<.001	53	view →
UVM	DFS	Tertile	All	0.556	0.821	.012	41	view →
READ	OS	Median	II,III,IV	1.000	0.820	.013	35	view →
COAD	OS	Median	All	0.702	0.417	.002	34	view →
STAD	OS	Quartile	II,III,IV	0.450	0.747	.009	21	view →
KIRP	OS	Median	All	0.593	0.891	.017	17	view →
OV	OS	Median	IV	0.468	0.274	.020	16	view →
LGG	DFS	Tertile	All	0.770	0.875	.003	14	view →
BRCA	OS	Quartile	II,III,IV	0.520	0.655	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

EIF4A1P4–UCS (DFS)

Open the UCS breakdown →