EIF3M

Across TCGA patient cohorts, EIF3M mutation is significantly associated with the RNA expression of many other genes, with 1,052 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF3M-associated genes across cancer lineages are MIR6803, SNX3P1Y, and PRAMEF13. Each is linked with EIF3M in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF3M-to-partner and partner-to-EIF3M results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by EIF3M-low versus EIF3M-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3M→partner) and Y-score (partner→EIF3M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.161	+4.571	<.001	.002	3	2
UCEC	SNX3P1Y →	+0.104	+4.571	<.001	.002	3	2
UCEC	PRAMEF13 →	+0.024	+3.231	<.001	.004	3	2
UCEC	RPS29P32 →	+0.555	+2.725	<.001	<.001	3	2
COAD	SYPL1P1 →	+0.111	+5.693	<.001	.003	3	2
LUSC	BCAS2P3 →	+0.064	+5.625	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,052 associations by consensus.

MIR6803 by EIF3M expression — UCEC

Explore this box plot interactively →