EIF3M

Across TCGA cell cohorts, EIF3M RNA expression is significantly associated with the go_rna of many other GO terms, with 3,169 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible EIF3M-associated GO terms across cancer lineages are Protein histidyl modification to diphthamide, Peptidyl-histidine modification, and Pyruvate decarboxylation to acetyl-CoA. Each is linked with EIF3M in more than 16 cancer types. Because this analysis shows association rather than direction, both EIF3M-to-partner and partner-to-EIF3M results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein histidyl modification to diphthamide grouped by EIF3M-low versus EIF3M-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3M→partner) and Y-score (partner→EIF3M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein histidyl modification to diphthamide →	+0.144	+1.043	<.001	<.001	3	17
OVARY	Peptidyl-histidine modification →	+0.144	+1.043	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Pyruvate decarboxylation to acetyl-CoA →	+0.143	+0.740	.002	.001	3	15
LUNG_SCLC	rRNA metabolic process →	+0.101	+0.570	.002	.007	2	13
SKIN	Ribosomal small subunit biogenesis →	+0.097	+0.552	<.001	<.001	3	12
SOFT_TISSUE	rRNA processing →	+0.091	+0.540	<.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,169 associations by consensus.

Protein histidyl modification to diphthamide by EIF3M expression — OVARY

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