EIF3LP1

Across TCGA patient cohorts, EIF3LP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,808 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF3LP1-associated GO terms across cancer lineages are Ribosomal large subunit export from nucleus, 5S class rRNA transcription by RNA polymerase III, and Ribosomal large subunit biogenesis. Each is linked with EIF3LP1 in more than 21 cancer types. Because this analysis shows association rather than direction, both EIF3LP1-to-partner and partner-to-EIF3LP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit export from nucleus grouped by EIF3LP1-low versus EIF3LP1-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3LP1→partner) and Y-score (partner→EIF3LP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Ribosomal large subunit export from nucleus →	+0.082	+0.451	<.001	<.001	3	22
LAML	5S class rRNA transcription by RNA polymerase III →	+0.062	+0.462	<.001	<.001	2	22
STAD	Ribosomal large subunit biogenesis →	+0.067	+0.167	<.001	<.001	3	20
LAML	Ribosomal small subunit biogenesis →	+0.059	+0.439	<.001	<.001	3	20
STAD	DNA-templated transcription initiation →	+0.055	+0.154	<.001	<.001	3	20
STAD	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.063	+0.130	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,808 associations by consensus.

Ribosomal large subunit export from nucleus by EIF3LP1 expression — LAML

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