EIF3L

Across TCGA patient cohorts, EIF3L RNA expression is significantly associated with the protein abundance of many other proteins, with 15,319 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF3L-associated proteins across cancer lineages are POLDIP3, XRCC5, and XRCC6. Each is linked with EIF3L in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF3L-to-partner and partner-to-EIF3L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3L versus POLDIP3 in GBM, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3L→partner) and Y-score (partner→EIF3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	POLDIP3 →	+0.329	+0.440	<.001	<.001	3	7
OV	XRCC5 →	+0.364	+0.922	<.001	<.001	3	7
OV	XRCC6 →	+0.396	+1.011	<.001	<.001	3	7
GBM	TNRC6B →	+0.230	+0.441	<.001	<.001	3	6
CCRCC	STAT2 →	-0.393	-0.423	<.001	<.001	3	6
LSCC	HELZ2 →	-0.426	-0.559	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,319 associations by consensus.

EIF3L vs POLDIP3 — GBM

Explore this scatter interactively →