EIF3L

Across TCGA patient cohorts, EIF3L protein abundance is significantly associated with the RNA expression of many other genes, with 17,577 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF3L-associated genes across cancer lineages are KIF11, CEP55, and SPARCL1. Each is linked with EIF3L in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF3L-to-partner and partner-to-EIF3L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3L versus KIF11 in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3L→partner) and Y-score (partner→EIF3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF11 →	+0.732	+0.111	.002	<.001	3	8
LUAD	CEP55 →	+0.802	+0.121	<.001	<.001	3	7
COAD	SPARCL1 →	-1.144	-0.137	<.001	<.001	3	7
LUAD	CDK1 →	+0.700	+0.125	<.001	<.001	3	7
CCRCC	GPIHBP1 →	-1.070	-0.122	<.001	<.001	3	7
PDAC	HELLS →	+0.609	+0.160	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,577 associations by consensus.

EIF3L vs KIF11 — UCEC

Explore this scatter interactively →