EIF3L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EIF3L protein abundance is significantly associated with the protein abundance of many other proteins, with 32,692 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EIF3L-associated proteins across cancer lineages are DDX21, DDX21_S89, and DRG1. Each is linked with EIF3L in more than 8 cancer types. Because this analysis shows association rather than direction, both EIF3L-to-partner and partner-to-EIF3L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3L versus DDX21 in LUAD, with a Pearson correlation of 0.65.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3L→partner) and Y-score (partner→EIF3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADDDX21 →+0.616+0.178<.001<.00139
LUADDDX21_S89 →+1.063+0.171<.001<.00139
LUADDRG1 →+0.231+0.157<.001<.00139
CCRCCEEF2 →+0.299+0.192<.001<.00139
LUADEIF3A →+0.231+0.234<.001<.00139
LUADEIF3B →+0.240+0.192<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 32,692 associations by consensus.

EIF3L vs DDX21 — LUAD

Per-sample scatter of EIF3L vs DDX21 in LUAD (Pearson r = 0.65).

Explore this scatter interactively →

Exploration