EIF3L

Across TCGA cell cohorts, EIF3L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,742 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible EIF3L-associated GO terms across cancer lineages are L-tryptophan catabolic process, Protein targeting to membrane, and Negative regulation of response to endoplasmic reticulum stress. Each is linked with EIF3L in more than 8 cancer types. Because this analysis shows association rather than direction, both EIF3L-to-partner and partner-to-EIF3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-tryptophan catabolic process grouped by EIF3L-low versus EIF3L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3L→partner) and Y-score (partner→EIF3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	L-tryptophan catabolic process →	+0.636	+0.622	.003	.001	3	9
BONE	Protein targeting to membrane →	-0.078	-0.641	<.001	.001	3	9
SOFT_TISSUE	Negative regulation of response to endoplasmic reticulum stress →	-0.088	-0.608	.001	.001	3	9
OESOPHAGUS	Transsulfuration →	+0.287	+0.847	<.001	.002	3	9
LIVER	RNA folding →	+0.090	+0.775	<.001	<.001	3	9
BONE	Indole-containing compound catabolic process →	+0.315	+0.700	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,742 associations by consensus.

L-tryptophan catabolic process by EIF3L expression — BONE

Explore this box plot interactively →