EIF3K

Across TCGA patient cohorts, EIF3K protein abundance is significantly associated with the RNA expression of many other genes, with 11,768 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EIF3K-associated genes across cancer lineages are NALCN, SEPTIN4, and ARHGEF9. Each is linked with EIF3K in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF3K-to-partner and partner-to-EIF3K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3K versus NALCN in GBM, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3K→partner) and Y-score (partner→EIF3K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NALCN →	-1.310	-0.159	<.001	<.001	3	7
CCRCC	SEPTIN4 →	-0.508	-0.105	.004	.006	3	6
HNSC	ARHGEF9 →	-0.469	-0.178	.002	<.001	3	6
HNSC	RAI2 →	-0.875	-0.227	<.001	<.001	3	6
LUAD	SLC1A7 →	-1.854	-0.160	<.001	<.001	3	6
OV	PRKD1 →	-1.048	-0.273	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,768 associations by consensus.

EIF3K vs NALCN — GBM

Explore this scatter interactively →