EIF3K

Across TCGA cell cohorts, EIF3K RNA expression is significantly associated with the go_rna of many other GO terms, with 2,689 significant associations in total. CNS shows the largest number of these associations.

The most reproducible EIF3K-associated GO terms across cancer lineages are Mitochondrial translation, Mitochondrial respiratory chain complex assembly, and Mitochondrial gene expression. Each is linked with EIF3K in more than 9 cancer types. Because this analysis shows association rather than direction, both EIF3K-to-partner and partner-to-EIF3K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by EIF3K-low versus EIF3K-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3K→partner) and Y-score (partner→EIF3K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Mitochondrial translation →	+0.074	+0.505	<.001	.004	3	10
SKIN	Mitochondrial respiratory chain complex assembly →	+0.069	+0.581	<.001	<.001	3	10
SKIN	Mitochondrial gene expression →	+0.076	+0.652	<.001	<.001	3	9
SKIN	Cytochrome complex assembly →	+0.048	+0.467	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Mitochondrial translational elongation →	+0.095	+1.030	.003	<.001	3	9
SOFT_TISSUE	snoRNA guided rRNA pseudouridine synthesis →	+0.088	+0.760	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,689 associations by consensus.

Mitochondrial translation by EIF3K expression — SKIN

Explore this box plot interactively →