EIF3IP1

Across TCGA pan-cancer cohorts, EIF3IP1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EIF3IP1 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher EIF3IP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated EIF3IP1 expression acts as an unfavorable survival marker.

ESCA, BRCA, and LUSC are the cancer types where EIF3IP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.161	0.707	<.001	42	view →
BRCA	OS	Median	All	0.027	0.963	<.001	36	view →
LUSC	OS	Median	III,IV	0.242	0.687	.020	12	view →
LIHC	OS	Median	All	0.268	0.690	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EIF3IP1–ESCA (OS)

Open the ESCA breakdown →