EIF3IP1

Across TCGA patient cohorts, EIF3IP1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EIF3IP1-associated genes across cancer lineages are Th2 cells, Melanocytes, and Adipocytes. Each is linked with EIF3IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF3IP1-to-partner and partner-to-EIF3IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by EIF3IP1-low versus EIF3IP1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3IP1→partner) and Y-score (partner→EIF3IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Th2 cells →	+0.181	+3.181	.041	.010	3	1
SKCM	Melanocytes →	+0.070	+2.201	.027	.034	3	1
LUAD	Adipocytes →	-0.016	-3.075	.044	.020	2	1
LUSC	DC →	-0.029	-2.976	.027	.037	1	2

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Th2 cells by EIF3IP1 expression — LUAD

Explore this box plot interactively →