EIF3G

Across TCGA cell cohorts, EIF3G RNA expression is significantly associated with the go_rna of many other GO terms, with 2,844 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EIF3G-associated GO terms across cancer lineages are rRNA metabolic process, Maturation of 5.8S rRNA, and snRNA transcription by RNA polymerase III. Each is linked with EIF3G in more than 10 cancer types. Because this analysis shows association rather than direction, both EIF3G-to-partner and partner-to-EIF3G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA metabolic process grouped by EIF3G-low versus EIF3G-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3G→partner) and Y-score (partner→EIF3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	rRNA metabolic process →	+0.087	+0.677	<.001	<.001	3	11
PANCREAS	Maturation of 5.8S rRNA →	+0.109	+0.700	<.001	<.001	3	11
PANCREAS	snRNA transcription by RNA polymerase III →	+0.070	+0.537	<.001	<.001	3	11
PANCREAS	rRNA processing →	+0.091	+0.653	<.001	.001	3	11
PANCREAS	Transcription by RNA polymerase III →	+0.084	+0.852	<.001	<.001	3	11
LUNG_SCLC	snRNA transcription by RNA polymerase II →	+0.093	+0.427	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,844 associations by consensus.

rRNA metabolic process by EIF3G expression — SKIN

Explore this box plot interactively →