EIF3FP3

Across TCGA pan-cancer cohorts, EIF3FP3 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated EIF3FP3 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher EIF3FP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EIF3FP3 expression acts as an unfavorable survival marker, although some lineages such as LGG and UCS show a favorable association.

ACC, LGG, and LIHC are the cancer types where EIF3FP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	II,III,IV	0.755	0.940	<.001	84	view →
LGG	DFS	Median	All	0.802	0.662	<.001	40	view →
LIHC	OS	Quartile	All	0.641	0.792	.006	37	view →
UCS	OS	Median	IV	0.817	0.302	.002	28	view →
LUAD	OS	Tertile	II,III,IV	0.556	0.804	.006	25	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	24	view →
KIRP	OS	Median	IV	0.040	0.525	.002	19	view →
COAD	OS	Median	IV	0.327	0.743	.002	14	view →
MESO	OS	Median	III,IV	0.483	0.283	.004	13	view →
OV	DFS	Tertile	II,III,IV	0.124	0.205	.017	12	view →
UCEC	DFS	Tertile	All	0.578	0.759	.023	12	view →
DLBC	DFS	Median	IV	0.510	1.000	.030	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

EIF3FP3–ACC (OS)

Open the ACC breakdown →