EIF3F

Across TCGA patient cohorts, EIF3F protein abundance is significantly associated with the RNA expression of many other genes, with 13,967 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EIF3F-associated genes across cancer lineages are HMGA1, SPATA6L, and SLC40A1. Each is linked with EIF3F in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF3F-to-partner and partner-to-EIF3F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3F versus HMGA1 in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3F→partner) and Y-score (partner→EIF3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HMGA1 →	+0.856	+0.179	<.001	<.001	3	6
CCRCC	SPATA6L →	-0.788	-0.150	<.001	<.001	3	5
BRCA	SLC40A1 →	-1.188	-0.117	.005	.007	3	5
COAD	N4BP2L1 →	-0.644	-0.197	.001	<.001	3	5
BRCA	AURKB →	+1.207	+0.188	<.001	<.001	3	5
GBM	BTBD8 →	-0.546	-0.136	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,967 associations by consensus.

EIF3F vs HMGA1 — GBM

Explore this scatter interactively →