EIF3F

Across TCGA patient cohorts, EIF3F mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible EIF3F-associated genes across cancer lineages are Mast cells, CD8+ naive T-cells, and Keratinocytes. Each is linked with EIF3F in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF3F-to-partner and partner-to-EIF3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mast cells grouped by EIF3F-low versus EIF3F-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3F→partner) and Y-score (partner→EIF3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Mast cells →	+0.016	+2.416	.036	.016	3	2
SKCM	CD8+ naive T-cells →	-0.028	-2.990	.030	.036	3	1
UCEC	Keratinocytes →	-0.018	-2.951	.015	.036	3	1
SKCM	Smooth muscle →	+0.112	+1.591	.018	.044	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Mast cells by EIF3F expression — SKCM

Explore this box plot interactively →