Across TCGA pan-cancer cohorts, EIF3EP2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of EIF3EP2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where EIF3EP2 RNA is repressed in tumor relative to normal tissue. In most cancer types EIF3EP2 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, BRCA, and THCA are the cancer types where EIF3EP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF3EP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	II,III,IV	−0.011	.039	2	view →
BRCA	Female	All	−0.004	.035	2	view →
THCA	All	II,III,IV	−0.020	.038	1	view →
LUAD	Male	All	+0.012	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: EIF3EP2 RNA expression & survival · all EIF3EP2 data types