EIF3E

Across TCGA patient cohorts, EIF3E protein abundance is significantly associated with the RNA expression of many other genes, with 18,166 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF3E-associated genes across cancer lineages are CYP2U1, NALCN, and SEPTIN4. Each is linked with EIF3E in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF3E-to-partner and partner-to-EIF3E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3E versus CYP2U1 in HNSC, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3E→partner) and Y-score (partner→EIF3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CYP2U1 →	-0.598	-0.171	<.001	<.001	3	8
GBM	NALCN →	-0.817	-0.108	<.001	<.001	3	7
GBM	SEPTIN4 →	-0.698	-0.135	<.001	<.001	3	7
COAD	MGP →	-2.228	-0.210	<.001	<.001	3	7
BRCA	LHFPL6 →	-0.907	-0.188	<.001	<.001	3	7
COAD	PLN →	-1.904	-0.208	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,166 associations by consensus.

EIF3E vs CYP2U1 — HNSC

Explore this scatter interactively →