EIF3D

Across TCGA patient cohorts, EIF3D protein abundance is significantly associated with the RNA expression of many other genes, with 15,483 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF3D-associated genes across cancer lineages are CXCR1, CXCR2, and CSF3R. Each is linked with EIF3D in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF3D-to-partner and partner-to-EIF3D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3D versus CXCR1 in PDAC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3D→partner) and Y-score (partner→EIF3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CXCR1 →	-1.010	-0.155	<.001	<.001	3	8
GBM	CXCR2 →	-0.957	-0.151	<.001	.001	2	8
UCEC	CSF3R →	-1.207	-0.215	<.001	<.001	3	6
BRCA	ACKR1 →	-1.735	-0.184	<.001	<.001	3	6
UCEC	RAPGEF3 →	-0.808	-0.123	<.001	.009	3	6
BRCA	LYVE1 →	-1.403	-0.191	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,483 associations by consensus.

EIF3D vs CXCR1 — PDAC

Explore this scatter interactively →