EIF3D

Across TCGA cell cohorts, EIF3D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,933 significant associations in total. CNS shows the largest number of these associations.

The most reproducible EIF3D-associated GO terms across cancer lineages are Positive regulation of mitochondrial fusion, XMP metabolic process, and XMP biosynthetic process. Each is linked with EIF3D in more than 13 cancer types. Because this analysis shows association rather than direction, both EIF3D-to-partner and partner-to-EIF3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial fusion grouped by EIF3D-low versus EIF3D-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3D→partner) and Y-score (partner→EIF3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of mitochondrial fusion →	+0.161	+0.525	<.001	.002	3	14
LUNG_SCLC	XMP metabolic process →	+0.139	+0.444	.001	.008	3	11
LUNG_SCLC	XMP biosynthetic process →	+0.139	+0.444	.001	.008	3	11
LUNG_SCLC	'de novo' XMP biosynthetic process →	+0.139	+0.444	.001	.008	3	11
LUNG_SCLC	Primitive hemopoiesis →	+0.134	+0.472	<.001	<.001	3	10
URINARY_TRACT	'de novo' IMP biosynthetic process →	+0.181	+0.861	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,933 associations by consensus.

Positive regulation of mitochondrial fusion by EIF3D expression — LUNG_SCLC

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