Across TCGA patient cohorts, EIF3C RNA expression is significantly associated with the protein abundance of many other proteins, with 10,770 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF3C-associated proteins across cancer lineages are TOP1, DHX9, and HEATR1. Each is linked with EIF3C in more than 4 cancer types. Because this analysis shows association rather than direction, both EIF3C-to-partner and partner-to-EIF3C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3C→partner) and Y-score (partner→EIF3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TOP1 →	+0.305	+0.383	.001	.002	3	5
LSCC	DHX9 →	+0.304	+0.596	<.001	<.001	3	4
LSCC	HEATR1 →	+0.397	+0.621	<.001	<.001	3	4
OV	WDR43_S77 →	+0.959	+0.771	<.001	<.001	3	4
LSCC	XPO5 →	+0.482	+0.533	<.001	<.001	3	4
OV	ZFC3H1_S206 →	+0.833	+0.706	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,770 associations by consensus.

Exploration

EIF3C survival (RNA) · tumor vs normal (RNA) · all EIF3C data types