Across TCGA cell cohorts, EIF3C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,973 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF3C-associated GO terms across cancer lineages are Mitochondrial disulfide relay system, Protein import into mitochondrial intermembrane space, and Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with EIF3C in more than 10 cancer types. Because this analysis shows association rather than direction, both EIF3C-to-partner and partner-to-EIF3C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3C→partner) and Y-score (partner→EIF3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Mitochondrial disulfide relay system →	+0.105	+0.878	<.001	<.001	3	11
OVARY	Protein import into mitochondrial intermembrane space →	+0.105	+0.974	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.093	+0.742	.001	.004	3	10
BLOOD_Myeloma	Formation of cytoplasmic translation initiation complex →	+0.092	+1.037	.004	<.001	3	10
BLOOD_Lymphoma	rRNA pseudouridine synthesis →	+0.088	+0.841	.001	<.001	3	8
LUNG_SCLC	Maturation of SSU-rRNA →	+0.106	+0.718	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,973 associations by consensus.

Exploration

EIF3C survival (RNA) · tumor vs normal (RNA) · all EIF3C data types