EIF3B

Across TCGA patient cohorts, EIF3B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,993 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF3B-associated proteins across cancer lineages are PUS7, FOXK1, and MSH2. Each is linked with EIF3B in more than 9 cancer types. Because this analysis shows association rather than direction, both EIF3B-to-partner and partner-to-EIF3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3B versus PUS7 in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3B→partner) and Y-score (partner→EIF3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PUS7 →	+0.619	+0.668	<.001	<.001	3	10
LSCC	FOXK1 →	+0.351	+0.493	<.001	<.001	3	9
GBM	MSH2 →	+0.479	+0.380	.001	<.001	3	8
BRCA	NOL11 →	+0.337	+0.388	<.001	<.001	3	8
BRCA	UTP4 →	+0.345	+0.367	<.001	<.001	3	8
BRCA	POLR1E →	+0.397	+0.366	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,993 associations by consensus.

EIF3B vs PUS7 — BRCA

Explore this scatter interactively →