EIF3B

Across TCGA patient cohorts, EIF3B protein abundance is significantly associated with the RNA expression of many other genes, with 15,985 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EIF3B-associated genes across cancer lineages are JAM2, PLPP3, and TLL1. Each is linked with EIF3B in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF3B-to-partner and partner-to-EIF3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3B versus JAM2 in BRCA, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3B→partner) and Y-score (partner→EIF3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	JAM2 →	-0.836	-0.149	<.001	<.001	3	7
BRCA	PLPP3 →	-0.693	-0.107	<.001	.002	3	7
CCRCC	TLL1 →	-0.802	-0.109	<.001	<.001	3	7
OV	ARHGDIB →	-0.953	-0.208	.007	.005	3	6
BRCA	KIF20A →	+0.839	+0.158	.001	<.001	3	6
BRCA	PLSCR4 →	-0.988	-0.183	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,985 associations by consensus.

EIF3B vs JAM2 — BRCA

Explore this scatter interactively →