EIF3A

Across TCGA patient cohorts, EIF3A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,788 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF3A-associated proteins across cancer lineages are SLK, MCMBP, and INPP5F. Each is linked with EIF3A in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF3A-to-partner and partner-to-EIF3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3A versus SLK in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3A→partner) and Y-score (partner→EIF3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLK →	+0.248	+0.347	<.001	<.001	3	7
HNSC	MCMBP →	+0.367	+0.793	<.001	<.001	3	6
BRCA	INPP5F →	+0.307	+0.401	.001	.001	3	5
LSCC	KIFBP →	+0.268	+0.404	<.001	<.001	3	5
UCEC	TIAL1 →	+0.187	+0.921	<.001	<.001	3	5
GBM	CTBP2 →	+0.346	+0.256	.003	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,788 associations by consensus.

EIF3A vs SLK — BRCA

Explore this scatter interactively →