EIF2S3B

Across TCGA patient cohorts, EIF2S3B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,015 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible EIF2S3B-associated GO terms across cancer lineages are Regulation of centriole replication, Positive regulation of mRNA metabolic process, and Protein modification by small protein removal. Each is linked with EIF2S3B in more than 28 cancer types. Because this analysis shows association rather than direction, both EIF2S3B-to-partner and partner-to-EIF2S3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole replication grouped by EIF2S3B-low versus EIF2S3B-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2S3B→partner) and Y-score (partner→EIF2S3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Regulation of centriole replication →	+0.094	+0.783	<.001	<.001	3	29
THYM	Positive regulation of mRNA metabolic process →	+0.043	+0.505	<.001	<.001	3	28
UCS	Protein modification by small protein removal →	+0.053	+0.702	<.001	.003	2	29
THYM	Regulation of cytoplasmic translation →	+0.060	+0.494	<.001	<.001	3	27
UCS	Regulation of autophagosome assembly →	+0.066	+1.039	<.001	<.001	3	27
DLBC	Centriole assembly →	+0.078	+0.775	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,015 associations by consensus.

Regulation of centriole replication by EIF2S3B expression — DLBC

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