EIF2S2P7

Across TCGA pan-cancer cohorts, EIF2S2P7 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated EIF2S2P7 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher EIF2S2P7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EIF2S2P7 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

ESCA, CESC, and STAD are the cancer types where EIF2S2P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
CESC	OS	Tertile	IV	0.091	0.593	<.001	36	view →
STAD	DFS	Tertile	IV	0.239	0.603	.019	32	view →
KIRC	DFS	Tertile	All	0.323	0.643	.002	24	view →
READ	DFS	Tertile	All	0.111	0.799	.001	18	view →
GBM	OS	Tertile	All	0.221	0.435	.022	18	view →
LUSC	DFS	Tertile	II,III,IV	0.233	0.672	.036	9	view →
UCEC	OS	Tertile	II,III,IV	0.732	0.859	.038	6	view →
LAML	DFS	Tertile	All	0.716	0.515	.046	4	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

EIF2S2P7–ESCA (OS)

Open the ESCA breakdown →