EIF2S2P1

Across TCGA pan-cancer cohorts, EIF2S2P1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated EIF2S2P1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher EIF2S2P1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated EIF2S2P1 expression acts as an unfavorable survival marker, although some lineages such as COAD and READ show a favorable association.

COAD, READ, and PAAD are the cancer types where EIF2S2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.933	0.805	.005	42	view →
READ	DFS	Median	II,III,IV	0.648	0.363	.002	40	view →
PAAD	DFS	Tertile	All	0.581	0.307	.015	36	view →
UCS	OS	Median	IV	0.817	0.302	.002	24	view →
SKCM	OS	Tertile	III,IV	0.866	0.600	.002	19	view →
GBM	OS	Quartile	All	0.326	0.572	.002	18	view →
LUSC	OS	Quartile	III,IV	0.304	0.883	.005	17	view →
ACC	OS	Median	III,IV	0.171	0.626	<.001	17	view →
DLBC	DFS	Tertile	IV	0.120	0.784	.045	6	view →
KIRP	OS	Quartile	II,III,IV	0.676	0.888	.027	4	view →
THCA	DFS	Tertile	III,IV	0.947	0.812	.048	3	view →
HNSC	OS	Tertile	II,III,IV	0.529	0.376	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

EIF2S2P1–COAD (OS)

Open the COAD breakdown →