EIF2S2

Across TCGA patient cohorts, EIF2S2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,732 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF2S2-associated proteins across cancer lineages are PAICS_S27, CSE1L, and AHCY. Each is linked with EIF2S2 in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF2S2-to-partner and partner-to-EIF2S2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2S2 versus PAICS_S27 in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2S2→partner) and Y-score (partner→EIF2S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PAICS_S27 →	+1.108	+1.053	<.001	<.001	3	8
LSCC	CSE1L →	+0.328	+0.444	<.001	<.001	3	7
LSCC	AHCY →	+0.404	+0.583	<.001	<.001	3	7
PDAC	EIF6 →	+0.433	+0.289	<.001	.003	3	7
LSCC	ESF1 →	+0.399	+0.542	<.001	<.001	3	7
UCEC	ESF1_S153 →	+1.010	+0.846	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,732 associations by consensus.

EIF2S2 vs PAICS_S27 — UCEC

Explore this scatter interactively →