EIF2S2

Across TCGA cell cohorts, EIF2S2 RNA expression is significantly associated with the RNA expression of many other genes, with 7,219 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible EIF2S2-associated genes across cancer lineages are ITCH, TARS1, and PFDN4. Each is linked with EIF2S2 in more than 16 cancer types. Because this analysis shows association rather than direction, both EIF2S2-to-partner and partner-to-EIF2S2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2S2 versus ITCH in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.62.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2S2→partner) and Y-score (partner→EIF2S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	ITCH →	+0.946	+0.727	.001	.002	3	17
BLOOD_Myeloma	TARS1 →	+1.076	+0.580	<.001	<.001	3	14
STOMACH	PFDN4 →	+1.370	+0.977	<.001	<.001	2	14
KIDNEY	PRELID3B →	+1.306	+0.898	<.001	<.001	3	13
BLOOD_Myeloma	DPM1 →	+1.066	+0.752	.002	<.001	2	14
BLOOD_Lymphoma	YARS1 →	+1.092	+0.803	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,219 associations by consensus.

EIF2S2 vs ITCH — LUNG_NSCLC_LUSC

Explore this scatter interactively →