EIF2S2

Across TCGA cell cohorts, EIF2S2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,695 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EIF2S2-associated GO terms across cancer lineages are Formate metabolic process, Cellular response to interleukin-12, and Response to interleukin-12. Each is linked with EIF2S2 in more than 11 cancer types. Because this analysis shows association rather than direction, both EIF2S2-to-partner and partner-to-EIF2S2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Formate metabolic process grouped by EIF2S2-low versus EIF2S2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2S2→partner) and Y-score (partner→EIF2S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Formate metabolic process →	+0.138	+0.711	<.001	.001	3	12
LUNG_SCLC	Cellular response to interleukin-12 →	-0.167	-0.451	.004	.006	3	10
LIVER	Response to interleukin-12 →	-0.201	-0.919	.006	.001	3	9
BREAST	Protein branched polyubiquitination →	+0.107	+0.640	<.001	.001	3	9
STOMACH	Formate biosynthetic process →	+0.127	+0.803	.001	.001	3	9
BREAST	Protein histidyl modification to diphthamide →	+0.083	+0.615	.008	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,695 associations by consensus.

Formate metabolic process by EIF2S2 expression — BLOOD_Lymphoma

Explore this box plot interactively →