EIF2B4

Across TCGA patient cohorts, EIF2B4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,961 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EIF2B4-associated genes across cancer lineages are SCN4B, CPED1, and MGP. Each is linked with EIF2B4 in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF2B4-to-partner and partner-to-EIF2B4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2B4 versus SCN4B in CCRCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2B4→partner) and Y-score (partner→EIF2B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SCN4B →	-0.823	-0.092	<.001	<.001	3	6
PDAC	CPED1 →	-0.646	-0.170	<.001	.005	3	5
OV	MGP →	-1.565	-0.216	<.001	<.001	3	5
OV	ABCA8 →	-1.109	-0.185	<.001	.002	3	5
OV	PRSS35 →	-0.699	-0.158	.005	.003	3	5
LUAD	LMOD1 →	-1.126	-0.202	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,961 associations by consensus.

EIF2B4 vs SCN4B — CCRCC

Explore this scatter interactively →