EIF2B3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EIF2B3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,900 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EIF2B3-associated genes across cancer lineages are DPH2, SNX9, and ADD3. Each is linked with EIF2B3 in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF2B3-to-partner and partner-to-EIF2B3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2B3 versus DPH2 in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2B3→partner) and Y-score (partner→EIF2B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDPH2 →+0.645+0.199<.001.00236
COADSNX9 →-0.347-0.133.006.00534
GBMADD3 →-0.668-0.199<.001<.00134
LSCCGNL2 →+0.482+0.184<.001<.00134
CCRCCTAL1 →-0.982-0.220<.001<.00134
CCRCCS1PR1 →-0.849-0.170.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,900 associations by consensus.

EIF2B3 vs DPH2 — OV

Per-sample scatter of EIF2B3 vs DPH2 in OV (Pearson r = 0.45).

Explore this scatter interactively →

Exploration