EIF2B3

Across TCGA patient cohorts, EIF2B3 mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF2B3-associated genes across cancer lineages are GMP, MPP, and Th2 cells. Each is linked with EIF2B3 in more than 2 cancer types. Because this analysis shows association rather than direction, both EIF2B3-to-partner and partner-to-EIF2B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by EIF2B3-low versus EIF2B3-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2B3→partner) and Y-score (partner→EIF2B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GMP →	+0.043	+4.264	.038	.024	3	3
STAD	MPP →	+0.016	+2.809	.021	.040	3	2
UCEC	Th2 cells →	+0.229	+2.008	.002	.018	3	2
STAD	Erythrocytes →	+0.020	+3.164	<.001	.032	3	1
UCEC	lymphatic Endothelial cells →	-0.019	-1.753	.047	.028	3	1
CESC	CD4+ Tem →	+0.001	+5.589	.005	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

GMP by EIF2B3 expression — LUSC

Explore this box plot interactively →