EIF2B2

Across TCGA patient cohorts, EIF2B2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,034 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EIF2B2-associated genes across cancer lineages are EIF2B3, ABCA6, and PHYHIP. Each is linked with EIF2B2 in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF2B2-to-partner and partner-to-EIF2B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2B2 versus EIF2B3 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2B2→partner) and Y-score (partner→EIF2B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EIF2B3 →	+0.418	+0.216	.001	.003	3	6
LUAD	ABCA6 →	-0.787	-0.158	<.001	<.001	3	5
GBM	PHYHIP →	-1.612	-0.205	<.001	<.001	3	5
OV	OLFML1 →	-0.706	-0.184	.002	<.001	3	5
OV	MAGI2-AS3 →	-0.876	-0.263	<.001	<.001	3	5
HNSC	MGP →	-1.003	-0.224	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,034 associations by consensus.

EIF2B2 vs EIF2B3 — OV

Explore this scatter interactively →