EIF2B2

Across TCGA cell cohorts, EIF2B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,438 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF2B2-associated GO terms across cancer lineages are Cellular response to manganese ion, Response to water-immersion restraint stress, and Protein depolymerization. Each is linked with EIF2B2 in more than 10 cancer types. Because this analysis shows association rather than direction, both EIF2B2-to-partner and partner-to-EIF2B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to manganese ion grouped by EIF2B2-low versus EIF2B2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2B2→partner) and Y-score (partner→EIF2B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Cellular response to manganese ion →	+0.115	+0.702	<.001	.001	3	11
SOFT_TISSUE	Response to water-immersion restraint stress →	-0.134	-0.976	.001	<.001	3	11
URINARY_TRACT	Protein depolymerization →	+0.154	+1.013	<.001	.002	3	11
BREAST	mRNA alternative polyadenylation →	+0.067	+0.764	.003	.002	2	11
PANCREAS	Nuclear histone mRNA catabolic process →	+0.097	+1.066	<.001	<.001	3	10
URINARY_TRACT	Response to manganese-induced endoplasmic reticulum stress →	+0.066	+0.864	.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

Cellular response to manganese ion by EIF2B2 expression — KIDNEY

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