EIF2B1

Across TCGA cell cohorts, EIF2B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,713 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF2B1-associated GO terms across cancer lineages are Transcription elongation-coupled chromatin remodeling, Translation reinitiation, and DNA-templated DNA replication maintenance of fidelity. Each is linked with EIF2B1 in more than 12 cancer types. Because this analysis shows association rather than direction, both EIF2B1-to-partner and partner-to-EIF2B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation-coupled chromatin remodeling grouped by EIF2B1-low versus EIF2B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2B1→partner) and Y-score (partner→EIF2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription elongation-coupled chromatin remodeling →	+0.132	+0.558	.002	.007	3	13
BLOOD_Myeloma	Translation reinitiation →	+0.107	+0.708	.003	.001	3	13
BLOOD_Lymphoma	DNA-templated DNA replication maintenance of fidelity →	+0.073	+0.668	<.001	<.001	3	12
BONE	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.137	+0.682	.001	<.001	3	12
OVARY	DNA-templated DNA replication →	+0.095	+0.505	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.088	+0.870	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,713 associations by consensus.

Transcription elongation-coupled chromatin remodeling by EIF2B1 expression — BONE

Explore this box plot interactively →