EIF2AK2

Across TCGA patient cohorts, EIF2AK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,568 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EIF2AK2-associated proteins across cancer lineages are OAS2, MX2, and XAF1. Each is linked with EIF2AK2 in more than 9 cancer types. Because this analysis shows association rather than direction, both EIF2AK2-to-partner and partner-to-EIF2AK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2AK2 versus OAS2 in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2AK2→partner) and Y-score (partner→EIF2AK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	OAS2 →	+0.870	+0.422	<.001	.002	3	10
GBM	MX2 →	+0.792	+0.550	<.001	<.001	3	10
GBM	XAF1 →	+0.802	+0.439	<.001	.005	3	9
OV	OAS3 →	+0.776	+0.939	<.001	<.001	3	9
PDAC	MX1 →	+1.190	+0.571	<.001	<.001	3	9
OV	IFIT1 →	+0.920	+0.928	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,568 associations by consensus.

EIF2AK2 vs OAS2 — GBM

Explore this scatter interactively →