EIF1B

Across TCGA cell cohorts, EIF1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,049 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible EIF1B-associated GO terms across cancer lineages are tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation, Protein localization to early endosome, and Chemokine (C-C motif) ligand 21 signaling pathway. Each is linked with EIF1B in more than 15 cancer types. Because this analysis shows association rather than direction, both EIF1B-to-partner and partner-to-EIF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation grouped by EIF1B-low versus EIF1B-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF1B→partner) and Y-score (partner→EIF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.154	+0.826	.002	.004	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to early endosome →	+0.175	+0.731	.004	.001	3	12
KIDNEY	Chemokine (C-C motif) ligand 21 signaling pathway →	+0.166	+1.198	.002	<.001	3	10
BONE	Positive regulation of neuromuscular junction development →	-0.250	-0.807	.003	<.001	2	10
URINARY_TRACT	Protein localization to non-motile cilium →	+0.060	+0.756	.007	.004	3	9
UPPER_AERODIGESTIVE_TRACT	tRNA 3'-terminal CCA addition →	+0.113	+0.682	.006	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,049 associations by consensus.

tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation by EIF1B expression — LIVER

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