Across TCGA pan-cancer cohorts, EIF1AY mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated EIF1AY data layer compared with 26 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher EIF1AY mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EIF1AY expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, HNSC, and PDAC are the cancer types where EIF1AY mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	1.000	0.373	.001	13	view →
HNSC	OS	Tertile	II,III,IV	0.928	1.000	.024	7	view →
PDAC	DFS	Median	All	0.885	0.658	.005	3	view →
CCRCC	OS	Tertile	All	0.728	0.961	.022	2	view →
LSCC	DFS	Median	III,IV	0.882	1.000	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: EIF1AY tumor-vs-normal RNA expression · all EIF1AY data types