EIF1AX

Across TCGA cell cohorts, EIF1AX RNA expression is significantly associated with the go_rna of many other GO terms, with 3,316 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF1AX-associated GO terms across cancer lineages are DNA replication initiation, DNA strand elongation, and Lagging strand elongation. Each is linked with EIF1AX in more than 16 cancer types. Because this analysis shows association rather than direction, both EIF1AX-to-partner and partner-to-EIF1AX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by EIF1AX-low versus EIF1AX-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF1AX→partner) and Y-score (partner→EIF1AX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication initiation →	+0.160	+0.964	.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.128	+0.888	.005	.007	2	17
LUNG_NSCLC_LUSC	Lagging strand elongation →	+0.188	+1.585	.002	<.001	3	15
OVARY	Regulation of chromosome segregation →	+0.114	+0.969	<.001	<.001	3	14
BLOOD_Myeloma	DNA replication →	+0.098	+0.885	<.001	.001	3	13
PANCREAS	Mitotic nuclear division →	+0.094	+0.976	<.001	.006	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,316 associations by consensus.

DNA replication initiation by EIF1AX expression — BLOOD_Myeloma

Explore this box plot interactively →