EIF1AX

Across TCGA cell cohorts, EIF1AX mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible EIF1AX-associated genes across cancer lineages are SERPINA7, C1orf158, and C3orf85. Each is linked with EIF1AX in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF1AX-to-partner and partner-to-EIF1AX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA7 grouped by EIF1AX-low versus EIF1AX-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF1AX→partner) and Y-score (partner→EIF1AX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1orf158 →	+0.053	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C3orf85 →	+0.103	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	OR4F6 →	+0.019	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SERPINA7 by EIF1AX expression — BLOOD_Myeloma

Explore this box plot interactively →