EIF1AD

Across TCGA pan-cancer cohorts, EIF1AD mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EIF1AD data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EIF1AD mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EIF1AD expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, COAD, and UCEC are the cancer types where EIF1AD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.969	0.859	.023	11	view →
COAD	DFS	Median	II,III,IV	0.843	1.000	.018	6	view →
UCEC	DFS	Median	III,IV	0.900	0.499	.025	6	view →
LSCC	OS	Tertile	All	0.678	1.000	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EIF1AD–HNSC (DFS)

Open the HNSC breakdown →