EIF1AD

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EIF1AD RNA expression is significantly associated with the go_rna of many other GO terms, with 3,621 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EIF1AD-associated GO terms across cancer lineages are Regulation of attachment of mitotic spindle microtubules to kinetochore, Positive regulation of attachment of mitotic spindle microtubules to kinetochore, and DNA-templated DNA replication maintenance of fidelity. Each is linked with EIF1AD in more than 14 cancer types. Because this analysis shows association rather than direction, both EIF1AD-to-partner and partner-to-EIF1AD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of attachment of mitotic spindle microtubules to kinetochore grouped by EIF1AD-low versus EIF1AD-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF1AD→partner) and Y-score (partner→EIF1AD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCRegulation of attachment of mitotic spindle microtubules to kinetochore →+0.202+0.947.001.003315
URINARY_TRACTPositive regulation of attachment of mitotic spindle microtubules to kinetochore →+0.194+0.815<.001.007314
BONEDNA-templated DNA replication maintenance of fidelity →+0.105+0.690.006<.001314
LARGE_INTESTINESpliceosomal tri-snRNP complex assembly →+0.092+0.678<.001<.001313
UPPER_AERODIGESTIVE_TRACTPositive regulation of mitotic cell cycle →+0.083+1.358.002<.001313
SOFT_TISSUEPositive regulation of attachment of spindle microtubules to kinetochore →+0.102+0.460<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,621 associations by consensus.

Regulation of attachment of mitotic spindle microtubules to kinetochore by EIF1AD expression — LUNG_NSCLC_LUSC

Box plot of Regulation of attachment of mitotic spindle microtubules to kinetochore in EIF1AD-low vs EIF1AD-high samples in LUNG_NSCLC_LUSC.

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Exploration