EIF1

Across TCGA patient cohorts, EIF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,411 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF1-associated proteins across cancer lineages are LIG3, CD74, and CHID1. Each is linked with EIF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF1-to-partner and partner-to-EIF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF1 versus LIG3 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF1→partner) and Y-score (partner→EIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LIG3 →	+0.419	+0.514	<.001	<.001	3	6
GBM	CD74 →	-0.590	-0.307	<.001	<.001	3	5
UCEC	CHID1 →	-0.329	-0.570	.001	.001	3	5
LSCC	RPUSD2 →	+0.171	+0.282	.003	.003	3	4
BRCA	RRBP1 →	-0.405	-0.432	.001	<.001	3	4
LSCC	RRP36_S73 →	+0.912	+0.605	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,411 associations by consensus.

EIF1 vs LIG3 — BRCA

Explore this scatter interactively →