EIF1

Across TCGA patient cohorts, EIF1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,748 significant associations in total. COAD shows the largest number of these associations.

The most reproducible EIF1-associated genes across cancer lineages are NEIL1, AXIN2, and DNAAF4. Each is linked with EIF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EIF1-to-partner and partner-to-EIF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF1 versus NEIL1 in CCRCC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF1→partner) and Y-score (partner→EIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NEIL1 →	-0.648	-0.197	<.001	.007	3	4
BRCA	AXIN2 →	-0.640	-0.322	.003	.004	3	4
OV	DNAAF4 →	-0.442	-0.375	<.001	.002	3	4
BRCA	TRIM3 →	-0.581	-0.233	.002	.002	3	4
LSCC	ZNF528-AS1 →	-0.603	-0.219	<.001	<.001	3	4
COAD	DLG4 →	-0.637	-0.348	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,748 associations by consensus.

EIF1 vs NEIL1 — CCRCC

Explore this scatter interactively →