EIF1

Across TCGA patient cohorts, EIF1 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,965 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF1-associated proteins across cancer lineages are RPS12, PSMA5, and EIF3I. Each is linked with EIF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF1-to-partner and partner-to-EIF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF1 versus RPS12 in PDAC, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF1→partner) and Y-score (partner→EIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RPS12 →	+0.433	+0.463	<.001	<.001	3	7
UCEC	PSMA5 →	+0.297	+0.351	<.001	.002	3	7
HNSC	EIF3I →	+0.294	+0.506	<.001	<.001	3	7
HNSC	EIF5 →	+0.397	+0.530	<.001	<.001	3	7
HNSC	ACTG1 →	+0.852	+0.495	<.001	<.001	3	6
HNSC	BTF3L4 →	+0.367	+0.337	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,965 associations by consensus.

EIF1 vs RPS12 — PDAC

Explore this scatter interactively →