EID2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EID2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EID2-associated genes across cancer lineages are USP9YP2, RN7SL763P, and RNA5SP133. Each is linked with EID2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EID2-to-partner and partner-to-EID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP2 grouped by EID2-low versus EID2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EID2→partner) and Y-score (partner→EID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECUSP9YP2 →+0.054+8.066<.001.00731
UCECRN7SL763P →+0.123+8.066<.001.00731
LUADRNA5SP133 →+0.394+7.930<.001.00831
LUADRNU6-793P →+0.439+7.930<.001.00831
LUADRNU1-142P →+0.569+7.930<.001.00831
LUADOR4M2 →+0.054+7.930<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

USP9YP2 by EID2 expression — UCEC

Box plot of USP9YP2 in EID2-low vs EID2-high samples in UCEC.

Explore this box plot interactively →

Exploration